Stability and crystal structures of His88 mutant human transthyretins

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His88, and His90) that are susceptible to protonation Wallaby TTR contains His56 and His88 conserved in its TTR sequence, however does not contain His31 or

his88 His88, and His90) that are susceptible to protonation Wallaby TTR contains His56 and His88 conserved in its TTR sequence, however does not contain His31 or

his88 They also induce the reorganisation of the His88 for coupling with other catalytic residues Another water molecule participate in inter-