p62 works as a hub modulation in the ageing process

p62 and NBR1 functions are dispensable for aggrephagy in mouse p62 app Molecular Psychiatry 2016 TLDR It is shown that increasing brain p62 expression rescues cognitive deficits in APPPS1 mice, a widely used animal model of AD p62com สล็อต Authors report protein p62 regulates beta amyloid turnover in APPPS1 mice Increasing p62, via gene therapy, rescues cognitive deficits in

p62 com สล็อต p62 is a well-characterized autophagy receptor that recognizes and sequesters specific cargoes into auto- phagosomes for degradation p62